2nd Workshop IMMUNO-model TGRC workshop Report

2nd Workshop IMMUNO-model TGRC workshop Report

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2nd Workshop IMMUNO-model TGRC workshop “Immunotherapies: charting a course from the lab to the clinic”, took place in Dublin City University, Ireland on Saturday, the 31st August 2024.

The workshop attendees heard from experts in the pre-clinical, clinical, translational and industry/SME sectors who provided presentations outlining their fields of expertise and the current challenges they face in relation to immunotherapies. The workshop opened with a welcome from Denis Collins, Ireland, and an overview of the COST Action by IMMUNO-model lead Eva Martinez-Balibrea, Spain, and WG3 Co-Lead Maurizio Callari, Italy. Two sessions followed.

The first session concentrated on best practice and current challenges with engaging presentations from David Pinato, UK, Emmet Mc Cormack, Norway and Samuel S. Chuang, Charles River Laboratories, USA on the clinical experience, in vivo models and the CRO setting, respectively. The second session explored beyond state-of-the-art approaches with contributions from Pedro Cruz, Portugal, Rita Fior, Portugal and Kristin Anderson, USA covering novel translational strategies, zebra fish models and engineered cellular therapies. The final session was led by the TGRC Committee members Catarina Rodrigues, Portugal, Hanne Haslene-Hox, Norway, Gianmarco Contino, UK, Uzma Hasa, France and Yari Ciribilli (Italy) and focussed on summarising the learnings from the first two sessions to identify new areas of research and the key challenges in modelling immunotherapy. Some of the key challenges identified included funding and better connections with clinicians and industry.

Number of participants: 55

Target audience: clinical and preclinical researchers in Oncology, Pharmacologists, Immunologists, Pathologists, advanced scientists, postdocs and PhD students and professionals working in immunotherapy and immuno-oncology field.

Scientific & Organizing Committee:

Denis Collins – CA21135 TGRC2 leader (denis.collins@dcu.ie)
Hanne Haslene-Hox – CA21135 TGRC3 leader (hanne.haslene-hox@sintef.no)
Gianmarco Contino – CA21135 TGRC1 leader (g.contino@bham.ac.uk)
Catarina A. Rodrigues – CA21135 TGRC2 coleader (crodrigues@ipatimup.pt)
Yari Ciribilli – CA21135 TGRC1 member (yari.ciribilli@unitn.it)
Hasan Uzma – CA21135 TGRC1 member (uzma.hasan@lyon.unicancer.fr)
Marta M. Bobińska – CA21135 TGRC3 member (marta.maleszewska@uw.edu.pl)

Program with topics
10:00-10:45‎‎‏‏‎
Registration of participants/Arrival of attendees/Tea, coffee, pastries
10:45 -11:00 ‎‏‏‎ ‎‏‏‎ ‎‏‏‎ ‎‏‏‎ ‎‏‏‎ ‎‏‏‎ ‎‏‏‎
Welcome Session
Denis Collins, Dublin City University, Ireland
11:00-11:15
IMMUNO-model – who we are, data collected to date
Eva Martinez-Balibrea, Catalan Institute of Oncology, Badalona, Spain
11:15-11:35
IMMUNO-model – working group experiences to date
Maurizio Callari, Fondazione Michelangelo, Italy
Session 1 – Best practice and current challenges
11:35-11:55
Immunotherapies in the Clinic
David Pinato, Imperial College London, UK
11:55-12:15
In vivo and in vitro models of Immunotherapies used in Academia
Emmet Mc Cormack, University of Bergen, Norway
12:15-12:35
In vivo and in vitro models of Immunotherapies used in Industry
Samuel S. Chuang, Charles River Laboratories, USA
12:35-13:05
Chaired open panel discussion with Session 1 speakers
13:05-14:00
Lunch
Session 2 – Beyond state of the art
14:00-14:20
Novel clinical & translational approaches
Pedro Cruz, IPO-Porto, Portugal
14:20-14:40
Novel in vivo approaches to modelling Immunotherapies
Rita Fior, Champalimaud Foundation, Portugal
14:40-15:00
Novel in vitro approaches to modelling Immunotherapies
Kristin Anderson, University of Virginia, USA
15:00-15:30
Chaired open panel discussion with Session 2 speakers
15:30-16:00
Coffee break and poster session
16:00-16:15
Summary of learnings from Sessions 1 and 2
Gianmarco Contino, University of Birmingham, UK
Hanne Haslene Hox, SINTEF, Norway
16:15-17:00
Chaired open panel discussion with attendees to outline key findings from the workshop & Closing Session
Catarina A. Rodrigues, IPO-Porto & i3S, Portugal
Yari Ciribilli, University of Trento, Italy

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